Instructor: Dr. Sondra Lazarowitz

            phone 5-7830

               Email: SGL5@cornell.edu
PLPA 606: Molecular Plant Virology: Class Schedule, Spring 2005
Class handouts: Readings:
Jan. 24           Basic Principles: Fundamental Differences Between Plant and Animal Viruses Jan 24
Replication and Gene Expression of Positive-Sense RNA Viruses:  
Jan. 26          Potyviruses: Polyprotein Strategy Jan 26
Jan. 31         Potexviruses: sgRNA and Leaky Ribosome Scanning Jan 31
Feb. 2           Tobamoviruses: sgRNA and Termination Suppression Feb 2
Feb. 7          Tymoviruses: sgRNA, polyprotein, and independent initiation Feb 7
Feb.  9            Luteoviruses: sgRNA, frameshift, leaky ribosome scanning, termination suppression, and polyprotein Feb 9
Feb. 14           Bromoviruses: multipartite, sgRNA Feb 14
Enveloped Viruses: Negative-Sense or Ambisense RNA Viruses  
Feb. 16          Feb. 16 Tospoviruses and Rhabdoviruses: Why does a plant virus need an envelope?
                              Exam I handed out in class.
 Feb 16
Viruses with DNA Genomes  
Feb. 21          Caulimoviruses (Exam I due in class): Reverse transcription Feb 21
Feb. 23         Geminiviruses: Host enzymes and a need for the nucleus Feb 23
Virus Movement  
Feb. 28          Cell-to-Cell Movement: Overview and Experimental Approaches
                          Journal Article and Questions handed-out for review.
 Feb 28
Mar. 2           Cell-to-Cell Movement: Mechanisms Mar 2
Mar. 7           Virus Systemic Movement (Critique of journal article due in class) Mar 7
Plant Responses to Viruses Infection  
Mar.  9          Host Resistance and Viral Counterstrategies
                           Final Exam handed out in class.
                          (FINAL EXAM DUE MARCH 14 AT NOON IN 359 PLANT SCIENCE)
Mar 9

EXAMS:
Your grade will be based on:

35%: A TAKE HOME EXAM handed out Feb. 16 and due Feb. 21

15%: A CRITIQUE of a scientific journal article (details to be discussed in class) handed out Feb. 28 and due Mar. 7.

50%: A TAKE HOME FINAL EXAM handed out Mar. 9 and due Mar. 14