Reading Assignment for April 15

click title to download the paper as a pdf file

K.M. Smith et al. 2008. The fungus Neurospora crassa displays telomeric silencing mediated
by multiple sirtuins and by methylation of histone H3 lysine 9. Epigenetics Chromatin 1:5. doi: 10.1186/1756-8935-1-5.

Please read the whole paper, and come prepared to present and discuss the section to which you are assigned (see below). Note the Materials & Methods section at the end (in smaller type) might be relevant to your bit. If you will not be able to attend on Wednesday at 1:25, please let us know so we can reassign your section.

Assignments:

Background Omer
Results AND associated Methods
Inactivation of nst genes Marin
Silencing of hph at Telomere VR  Tiffany
Silencing of bar at Telomere VIIL Christine
Inhibitors of HDACs relieve telomeric silencing  Stephen
NST activity Dan
DNA methylation of subtelomeric regions Bradford
Histone modifications associated with silent telomeric regions  Shawn
Discussion Everyone

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